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ChemicalBook >> CAS DataBase List >>Tetrasodium pyrophosphate

Tetrasodium pyrophosphate

Chemical Name:
Tetrasodium pyrophosphate
pyrophosphate;TSPP;SODIUM DIPHOSPHATE DECAHYDRATE;Anhydrous sodium pyrophosphate;pyro;SODIUM TETRAPYROPHOSPHATE;sodiumpyrophosphate[na4p2o7];tetrasodiumpyrophosphate,anhydrous;Nsc56751;victortspp
Molecular Formula:
Molecular Weight:
MDL Number:
MOL File:
MSDS File:
Last updated:2023-08-15 17:37:19

Tetrasodium pyrophosphate Properties

Melting point 80 °C
Boiling point 93.8 °C
Density 2.53 g/mL at 25 °C(lit.)
vapor pressure 0Pa at 20℃
storage temp. Inert atmosphere,Room Temperature
solubility H2O: 0.1 M at 20 °C, clear, colorless
form Granular
color White
Specific Gravity 2.534
Odor Odorless
PH Range 10.3
Water Solubility Soluble in water. Insoluble in ethyl alcohol.
Sensitive Hygroscopic
Merck 14,9240
Exposure limits NIOSH: TWA 5 mg/m3
Stability Stable. Incompatible with strong oxidizing agents.
LogP -3.42
FDA 21 CFR 182.6787; 182.6789; 582.6787; 582.6789; 173.310; 175.210; 175.300; 181.29; 182.70
Substances Added to Food (formerly EAFUS) SODIUM PYROPHOSPHATE
SCOGS (Select Committee on GRAS Substances) Sodium pyrophosphate, tetrabasic
CAS DataBase Reference 7722-88-5(CAS DataBase Reference)
EWG's Food Scores 1
EPA Substance Registry System Tetrasodium pyrophosphate (7722-88-5)


Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
Signal word  Danger
Hazard statements  H318
Precautionary statements  P280-P305+P351+P338
Hazard Codes  Xi,Xn
Risk Statements  36/37/38-41-22
Safety Statements  26-36-39
WGK Germany  3
RTECS  UX7350000
HS Code  28353990
NFPA 704
2 1

Tetrasodium pyrophosphate price More Price(13)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich P8010 Sodium pyrophosphate tetrabasic ≥95% 7722-88-5 500g $48.8 2023-06-20 Buy
Sigma-Aldrich P8010 Sodium pyrophosphate tetrabasic ≥95% 7722-88-5 2.5kg $225 2023-06-20 Buy
Alfa Aesar 013439 Sodium pyrophosphate, anhydrous tech. 7722-88-5 250g $37.5 2023-06-20 Buy
Alfa Aesar 013439 Sodium pyrophosphate, anhydrous tech. 7722-88-5 1kg $74 2023-06-20 Buy
Alfa Aesar A17546 Sodium pyrophosphate 98% 7722-88-5 250g $37.4 2023-06-20 Buy
Product number Packaging Price Buy
P8010 500g $48.8 Buy
P8010 2.5kg $225 Buy
013439 250g $37.5 Buy
013439 1kg $74 Buy
A17546 250g $37.4 Buy

Tetrasodium pyrophosphate Chemical Properties,Uses,Production


Sodium pyrophosphate, also called Tetrasodium pyrophosphate or TSPP is used in the laboratory as a buffering agent. The compound has been shown to be useful in the preparation of an EDTA-sodium pyrophosphate extraction buffer for microcystin analysis of soil samples. Tetrasodium pyrophosphate is an odorless, white powder or granules. It is used in water softener, buffering agent, thickening agent, dispersing agent, wool de-fatting agent, metal cleaner, soap and synthetic detergent builder, general sequestering agent, in electrodeposition of metals. It also acts as a tartar control agent in toothpaste and dental floss. In addition, it is used as a chelating agent in antimicrobial studies. It is also used as a food additive in common foods such as chicken nuggets, crab meat and canned tuna.

Chemical Properties

Tetrasodium pyrophosphate is a white crystalline powder or colourless crystals with the formula Na4P2O7. It contains the pyrophosphate ion and sodium cation. Toxicity is approximately twice that of table salt when ingested orally. There is also a hydrated form, Na4P2O7.10H2O.
Tetrasodium pyrophosphate
Tetrasodium pyrophosphate is used as a buffering agent, an emulsifier, a dispersing agent, and a thickening agent, and is often used as a food additive. It is widely used as an emulsifying salt (ES) in process cheese. Common foods containing sodium pyrophosphate include chicken nuggets, marshmallows, pudding, crab meat, imitation crab, canned tuna, and soy-based meat alternatives and cat foods and cat treats where it is used as a palatability enhancer. It is the active ingredient in Bakewell, the substitute for baking powder's acid component marketed during shortages in World War II. It is also used in some common baking powders.


Pharmaceutic aid.
Tetrasodium pyrophosphate (Na4P2O7) is a non-toxic and biocompatible compound used as an electroactive media for exfoliation of the surface coating. It is also be used as an additive in the food industry.
Na4P2O7 can be used as an inorganic additive to improve the stability and electrochemical performance of redox flow batteries.


Tetrasodium Pyrophosphate is a coagulant, emulsifier, and sequestrant that is mildly alkaline, with a ph of 10. it is moderately soluble in water, with a solubility of 0.8 g/100 ml at 25°c. it is used as a coagulant in noncooked instant puddings to provide thicken- ing. it functions in cheese to reduce the meltability and fat separa- tion. it is used as a dispersant in malted milk and chocolate drink powders. it prevents crystal formation in tuna. it is also termed sodium pyrophosphate, tetrasodium diphosphate, and tspp.


As a water softener; as a metal cleaner; as a dispersing and emulsifying agent.


ChEBI: Sodium diphosphate is an inorganic sodium salt comprised of a diphosphate(4-) anion and four sodium(1+) cations. More commonly known as tetrasodium pyrophosphate, it finds much use in the food industry as an emulsifier and in dental hygiene as a calcium-chelating salt. It has a role as a food emulsifier, a chelator and a food thickening agent. It contains a diphosphate(4-).


Tetrasodium pyrophosphate is formed when pure disodium hydrogen orthophosphate is heated to 500℃ for 5 hours. The product will contain better than 98 per cent Na4P2O7. Crystalline masses large enough for optical measurements are produced by heating in platinum to above the melting point of the tetrasodium pyrophosphate, 800°, and cooling slowly. Higher temperatures or longer heating times do not change the tetrasodium pyrophosphate, as this is the final product in the dehydration of disodium hydrogen orthophosphate.

General Description

Odorless, white powder or granules. Mp: 995°C. Density: 2.53 g cm-3. Solubility in water: 3.16 g / 100 mL (cold water); 40.26 g / 100 mL boiling water. Used as a wool de-fatting agent, in bleaching operations, as a food additive. The related substance Tetrasodium pyrophosphate decahydrate (Na4P2O7 0H2O) occurs as colorless transparent crystals. Loses its water when heated to 93.8°C.

Reactivity Profile

Tetrasodium pyrophosphate is basic. Reacts exothermically with acids. Incompatible with strong oxidizing agents. Decomposes in ethyl alcohol.


Toxic by inhalation.

Health Hazard

Tetrasodium pyrophosphate (TSPP) is of low toxicity, but the dust may be irritating to the eyes, upper respiratory tract, and skin. Mild to moderate skin and eye irritation have occurred with acute exposure to the dust.

Safety Profile

Poison by ingestion, intraperitoneal, intravenous, and subcutaneous routes. It is not a cholinesterase inhibitor. When heated to decomposition it emits toxic fumes of POx and Na2O.

Global( 466)Suppliers
Supplier Tel Email Country ProdList Advantage
Chongqing Chuandong Chemical (Group) Co. Ltd.
+86-13637972665 +86-13637972665 wxc@cd1958.com China 81 58
Wuhan Pinestone Fortune International Trading Co., Ltd.
+86-027-85615902 +86-13971435335 imp.exp8@fengfan.net China 29 58
Jiangsu Kolod Food Ingredients Co.,Ltd.
+86-518-85110578 +8618805133257 sales3257@jskolod.com China 130 60
Henan Tianfu Chemical Co.,Ltd.
+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21719 55
Hefei TNJ Chemical Industry Co.,Ltd.
+86-0551-65418679 +86-18949832763 info@tnjchem.com China 2990 55
career henan chemical co
+86-0371-86658258 sales@coreychem.com China 29920 58
Hubei Jusheng Technology Co.,Ltd.
18871490254 linda@hubeijusheng.com CHINA 28181 58
Hebei Guanlang Biotechnology Co., Ltd.
+86-19930503282 alice@crovellbio.com China 8835 58
Chongqing Chemdad Co., Ltd
+86-023-61398051 +8613650506873 sales@chemdad.com China 39917 58
Shaanxi Dideu Medichem Co. Ltd
+8618192503167 1006@dideu.com China 3965 58

Related articles

View Lastest Price from Tetrasodium pyrophosphate manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Tetrasodium pyrophosphate pictures 2023-08-15 Tetrasodium pyrophosphate
US $0.00-0.00 / kg 1kg 0.99 50000kg Hebei Yibangte Import and Export Co. , Ltd.
Tetrasodium pyrophosphate pictures 2023-03-06 Tetrasodium pyrophosphate
US $2.60 / KG 1KG 99.5% 5000kg Hebei Crovell Biotech Co Ltd
Tetrasodium pyrophosphate pictures 2023-02-01 Tetrasodium pyrophosphate
US $0.00 / KG 1KG 98%min 30tons/month WUHAN FORTUNA CHEMICAL CO., LTD
pyrophosphatedesodium jiaolinsuanan pyrophosphatetetrasodique Sodiumpyrophosphate,anhydrous sodiumpyrophosphate[na4p2o7] tetranatriumpyrophosphat tetrasodiumpyrophosphate,anhydrous victortspp Tetrasodium phosphonato phosphate Diphosphoric acid tetrasodium Sodium Pyrophosphate(Anhidride) SODIUM DI Nsc56751 Pyrophosphate sodium salt SodiuM Pyrophosphate Anhydrous FCC SODIUM PYROPHOSPHAYE Sodium pyrophosphate tetrabasic Vetec(TM) reagent grade, 95% SodiuM pyrophosphate tetrabasic >=95% Food Grade Sodium Pyrophosphate Anhydrous DIPHOSPHORIC ACID TETRASODIUM SALT DIPHOSPHORIC ACID, TETRASODIUM SALT, DECAHYDRATE DECAHYDRATE TETRASODIUM PYROPHOSPHATE TETRA-SODIUM DIPHOSPHATE TETRA-SODIUM DIPHOSPHATE-10-HYDRATE TETRA-SODIUM DIPHOSPHATE DECAHYDRATE TETRASODIUM PYROPHOSPHATE SODIUM DIPHOSPHATE SODIUM DIPHOSPHATE DECAHYDRATE SODIUM DIPHOSPHATE TETRABASIC DECAHYDRATE Sodium phosphate (pyro) PYROPHOSPHATE TETRASODIUM Sodium pyrophosphate tetrabasic anhydrous TetraSodiumPyrophosphateFoodGradeAnhydrous TetraSodiumPyrophosphateTechGradeAnhydrous Tetra-SodiumPyrophosphate(Anhydrous)E.P. sodium diphosphate tetrabasic sodium pyrophosphate tetrabasic sodium pyrophosphate, anhydrous, tech. SODIUMPYROPHOSPHATE,ANHYDROUS,POWDER,FCC phosphonooxyphosphonic acid Sodium Pyrophosphate Tetra, 10-Hydrate Sodium diphosphate tetrabasic, Tetrasodium pyrophosphate sodium pyophosphate,anhydrous for food anhydroustetrasodiumpyrophosphate natriumpyrophosphat phosphotex pyro pyrophosphate SODIUM PYROPHOSPHATE, 10-HYDRATE SODIUM PYROPHOSPHATE TETRABASIC DECAHYDRATE SODIUM TETRAPYROPHOSPHATE PYROPHOSPHATE INORGANIC Pyrophosphoric acid,tetrasodiumsalt TSPP Diphosphoric acid, sodium salt (1:4) Sodium pyrophosphate, 99%, for synthesis Tetrasodium pyrophosphate ISO 9001:2015 REACH Sodium pyrophosphate(v)
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